The National Travel Health Network and Centre (NaTHNaC) has passed on confirmation from Chile’s Ministry of Health of the first case of autochtonous (locally acquired) Zika virus (ZIKV) in a resident of Easter Island, a Chilean territory in the Pacific Ocean. The case was first identified on 28 January, although confirmation has only recently been announced. Dengue fever is endemic on Easter Island, transmitted by the Aedes aegypti mosquito, which is the same mosquito vector that transmits ZIKV, and public health responses on the island are reportedly underway. ZIKV’s symptoms include fever, headache, maculo-papular rash, conjunctivitis and pain in the smaller joints of the hands and feet. The illness is usually mild and short lasting – currently, there is no vaccine.